Chris Somerville|Heather Youngs money moved

This is an online portal with information on donations that were announced publicly (or have been shared with permission) that were of interest to Vipul Naik. The git repository with the code for this portal, as well as all the underlying data, is available on GitHub. All payment amounts are in current United States dollars (USD). The repository of donations is being seeded with an initial collation by Issa Rice as well as continued contributions from him (see his commits and the contract work page listing all financially compensated contributions to the site) but all responsibility for errors and inaccuracies belongs to Vipul Naik. Current data is preliminary and has not been completely vetted and normalized; if sharing a link to this site or any page on this site, please include the caveat that the data is preliminary (if you want to share without including caveats, please check with Vipul Naik). We expect to have completed the first round of development by the end of March 2023. See the about page for more details. Also of interest: pageview data on analytics.vipulnaik.com, tutorial in README, request for feedback to EA Forum.

Table of contents

Full list of documents in reverse chronological order (4 documents)

Title (URL linked)Publication dateAuthorPublisherAffected donorsAffected doneesDocument scopeNotes
Suggestions for Individual Donors from Open Philanthropy Staff - 20192019-12-18Holden Karnofsky Open PhilanthropyChloe Cockburn Jesse Rothman Michelle Crentsil Amanda Hungerfold Lewis Bollard Persis Eskander Alexander Berger Chris Somerville Heather Youngs Claire Zabel National Council for Incarcerated and Formerly Incarcerated Women and Girls Life Comes From It Worth Rises Wild Animal Initiative Sinergia Animal Center for Global Development International Refugee Assistance Project California YIMBY Engineers Without Borders 80,000 Hours Centre for Effective Altruism Future of Humanity Institute Global Priorities Institute Machine Intelligence Research Institute Ought Donation suggestion listContinuing an annual tradition started in 2015, Open Philanthropy Project staff share suggestions for places that people interested in specific cause areas may consider donating. The sections are roughly based on the focus areas used by Open Phil internally, with the contributors to each section being the Open Phil staff who work in that focus area. Each recommendation includes a "Why we recommend it" or "Why we suggest it" section, and with the exception of the criminal justice reform recommendations, each recommendation includes a "Why we haven't fully funded it" section. Section 5, Assorted recomendations by Claire Zabel, includes a list of "Organizations supported by our Committed for Effective Altruism Support" which includes a list of organizations that are wiithin the purview of the Committee for Effective Altruism Support. The section is approved by the committee and represents their views.
Explaining Our Bet on Sherlock Biosciences’ Innovations in Viral Diagnostics2019-06-10Heather Youngs Chris Somerville Open PhilanthropyOpen Philanthropy Sherlock Biosciences Single donation documentationIn this new-style blog post, the reasons for the Open Philanthropy Project grant https://www.openphilanthropy.org/focus/scientific-research/miscellaneous/sherlock-biosciences-research-viral-diagnostics to Sherlock Biosciences are explained in a conversational style. The conversation participants include Michael Levine (Communications Officer) and the grant investigators Chris Somerville and Heather Youngs.
Our ‘Second Chance’ Program for NIH Transformative Research Applicants2017-12-20Heather Youngs Open PhilanthropyOpen Philanthropy Arizona State University University of Notre Dame Rockefeller University Univesity of California San Francisco Broad donor strategyThe blog post describes a "second chance" program that the Open Philanthropy Project ran for rejected applications to the National Institutes of Health transformative R01 program https://commonfund.nih.gov/tra Four grants were made based on this, totaling $10.8 million. The grants were also covered in Nature at https://www.nature.com/articles/d41586-017-08795-0
Staff members’ personal donations for giving season 20162016-12-09Natalie Crispin GiveWellElie Hassenfeld Holden Karnofsky Natalie Crispin Alexander Berger Timothy Telleen-Lawton Josh Rosenberg Rebecca Raible Helen Toner Sophie Monahan Laura Muñoz Catherine Hollander Andrew Martin Lewis Bollard Chelsea Tabart Sarah Ward Chris Somerville Ajeya Cotra Chris Smith Isabel Arjmand A political campaign GiveWell top charities International Genetically Engineered Machine Foundation UPMC Center for Health Security Donor lottery EA Giving Group GiveDirectly Center for Applied Rationality Malaria Consortium Animal Charity Evaluators Northwest Health Law Advocates StrongMinds Against Malaria Foundation Schistosomiasis Control Initiative The Humane Society of the United States The Humane League Mercy For Animals Humane Society International Compassion in World Farming USA The Good Food Institute Citizens for Farm Animal Protection END Fund Causa Justa Planned Parenthood International Refugee Assistance Project Periodic donation list documentationGiveWell and Open Philanthropy Project staff describe their annual donation plans for 2016. Some of these are tentative and get superseded by further events. Also, not all employees are present in the document (participation is optional). Amounts donated are not included, per a decision by GiveWell

Full list of donations in reverse chronological order (34 donations)

DonorDoneeAmount (current USD)Donation dateCause areaURLNotes
Open PhilanthropyFoundation for Food and Agricultural Research444,000.002020-06Animal welfare/meat alternatives/plant-based meathttps://www.openphilanthropy.org/focus/us-policy/farm-animal-welfare/foundation-food-and-agriculture-research-chickpea-and-corn-zein-research Donation process: The grant funds proposals received in response to the request for proposals from FFAR co-funded by an April 2020 grant https://www.openphilanthropy.org/focus/us-policy/farm-animal-welfare/foundation-food-and-agriculture-research-farm-animal-welfare-research-2020 from Open Phil. Also worth noting: one of the grant investigators (Chris Somerville) is one of Open Phil's scientific advisors and he does not usually investigate animal welfare grants. Moreover, one portion of the grant is matched with a grant from the scientific researcch program.

Intended use of funds (category): Direct project expenses

Intended use of funds: Grant "to support protein optimization in chickpeas, led by NuCicer, and research into improving corn zein’s functionality for plant-based meat, led by Professor Bruce Hamaker of Purdue University." The chickpea portion of this research represents a match of a similar grant https://www.openphilanthropy.org/focus/scientific-research/foundation-for-food-and-agriculture-research-plant-protein-optimization-research from the scientific research program.

Donor reason for donating that amount (rather than a bigger or smaller amount): The amount is likely determined by the specifics of the proposals submitted.

Donor reason for donating at this time (rather than earlier or later): The grant funds proposals submitted in response to a request for proposals co-funded two months ago. The timing of the grant is likely determined by the timing of the original request for proposals.
Intended funding timeframe in months: 36
Open PhilanthropyCalifornia Institute of Technology2,000,000.002019-07Scientific research/transformative basic sciencehttps://www.openphilanthropy.org/focus/scientific-research/california-institute-technology-research-reproductive-biology-magdalena-zernicka-goetz Intended use of funds (category): Direct project expenses

Intended use of funds: The grant page says the grant is "to support research by Professor Magdalena Zernicka-Goetz on reproductive biology. Dr. Zernicka-Goetz’s proposed research would focus on understanding the molecular processes by which a single cell gives rise to all of the cell types and organ/tissue structures that comprise a fully developed embryo."

Donor reason for selecting the donee: The grant page says: "Progress in this area could eventually enable people with fertility challenges to have children and could eventually help reduce the incidence of a wide variety of high-burden disorders (such as heart disease, chronic pain, depression, and Alzheimer’s disease) and promote other positive outcomes. Dr. Zernicka-Goetz’s research is amongst the most promising our science team has encountered so far in this field."

Other notes: Intended funding timeframe in months: 48; announced: 2019-09-05.
Open PhilanthropyEngineers Without Borders USA500,000.002019-05Scientific research/human health and wellbeinghttps://www.openphilanthropy.org/focus/scientific-research/human-health-and-wellbeing/engineers-without-borders-off-grid-refrigeration Donation process: Discretionary grant

Intended use of funds (category): Direct project expenses

Intended use of funds: Grant "to support the Affordable Off-Grid Refrigeration Challenge. The competition will seek to develop proof of concept prototypes for refrigerators and ice-makers that have the potential to provide sustainable and affordable refrigeration for off-grid, developing world communities. Engineers Without Borders USA believes that affordable off-grid refrigeration will help reduce illnesses and deaths from vaccine-preventable diseases, food poisoning, and malnutrition, and that making refrigeration more widely available will also diminish food waste, enable small farmers to grow higher value crops, and reduce the burden on women by eliminating the need to travel to the market daily for perishable food."

Donor reason for selecting the donee: Grant made for the goal of advancing human health and wellbeing, and likely for the same reasons that the grantee thinks the project has value, namely: "affordable off-grid refrigeration will help reduce illnesses and deaths from vaccine-preventable diseases, food poisoning, and malnutrition, and that making refrigeration more widely available will also diminish food waste, enable small farmers to grow higher value crops, and reduce the burden on women by eliminating the need to travel to the market daily for perishable food."

Other notes: Announced: 2019-07-19.
Open PhilanthropyLife Sciences Research Foundation1,170,000.002019-04Scientific research/trasnformative basic sciencehttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/life-sciences-research-foundation-young-investigators-2019 Donation process: Discretionary grant

Intended use of funds (category): Direct project expenses

Intended use of funds: The grant page says: "The funds will support six postdoctoral fellows for three years apiece. The fellows have proposed research projects investigating Alzheimer’s disease, infectious disease dynamics, forebrain development, cross-species transmission of bird flu, muscle stem cell function, and immune system evolution."

Other notes: Intended funding timeframe in months: 36; announced: 2019-06-26.
Open PhilanthropyUniversity of California, Los Angeles2,368,300.002019-04Scientific research/transformative basic sciencehttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/ucla-epigenetic-clock-research Intended use of funds (category): Direct project expenses

Intended use of funds: Grant "to UCLA Professor Steve Horvath and collaborators to pursue a series of experiments directed toward understanding why an algorithm based on the presence or absence of epigenetic modifications at several hundred sites in the human genome, which they call the “epigenetic clock,” is able to predict age with very high accuracy. Dr. Horvath and his collaborators plan to systematically alter the activity of genes that are thought to affect the clock in mice, to test whether they can slow or accelerate the clock and, if they can, what effects perturbation of the clock may have on the aging processes in the mice. They will also investigate why some human syndromes are associated with accelerated aging, and will study how the clock works in various types of cultured human cells."

Donor reason for selecting the donee: The grant page says "The research will seek to understand how the clock measures age and whether changes to the associated processes can have useful impact on aging in humans."

Other notes: Intended funding timeframe in months: 36; announced: 2019-06-22.
Open PhilanthropyRita Allen Foundation495,000.002019-04Scientific research/human health and wellbeing/pain studieshttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/rita-allen-foundation-fellowship-support Donation process: Discretionary grant

Intended use of funds (category): Direct project expenses

Intended use of funds: Grant to provide three years in flexible support to three scholars identified by the American Pain Society in collaboration with the Rita Allen Foundation as excellent researchers in the fields of pain, neuroscience, anesthesiology and neurology. The scholars are: Jordan McCall, assistant professor, Washington University St. Louis; Peter Grace, assistant professor, MD Anderson Center Texas; and Vivianne Tawfik, assistant professor, Stanford University.

Donor reason for donating that amount (rather than a bigger or smaller amount): Amount likely determined by the number of researchers being funded and the total cost of funding them for three years. No explicit discussion of reason for amount on the grant page

Other notes: Intended funding timeframe in months: 36; announced: 2019-06-26.
Open PhilanthropyKyoto University4,000,000.002019-04Scientific research/transformative basic science/stem cell researchhttps://www.openphilanthropy.org/giving/grants/kyoto-university-research-reproductive-biology-mitinori-saitou Grant to support research by Professor Mitinori Saitou on reproductive biology. Dr. Saitou has been at the forefront of research into methods of causing induced pluripotent stem cells to develop into oocytes in mice. Progress in this area could eventually enable people with fertility challenges to have children and could eventually help reduce the incidence of a wide variety of high-burden disorders (such as heart disease, chronic pain, depression, and Alzheimer’s disease) and lead to other beneficial outcomes. Announced: 2019-04-23.
Open PhilanthropyUniversity of Michigan2,500,000.002019-03Scientific research/transformative basic sciencehttps://www.openphilanthropy.org/focus/scientific-research/university-michigan-research-on-mammalian-gamete-development Intended use of funds (category): Direct project expenses

Intended use of funds: Grant to support research by Professor Sue Hammoud on mammalian gamete development. Dr. Hammoud’s proposed research would be specifically focused on development of gametes from stem cells.

Donor reason for selecting the donee: The grant page says: "Progress in this area could eventually enable people with fertility challenges to have children and could eventually help reduce the incidence of a wide variety of high-burden disorders (such as heart disease, chronic pain, depression, and Alzheimer’s disease) and promote other positive outcomes. Dr. Hammoud’s research is amongst the most promising our science team has encountered so far in this field." The grant follows up on an April 2016 grant https://www.openphilanthropy.org/focus/scientific-research/miscellaneous/university-southern-california-genomic-research-methods

Other notes: Intended funding timeframe in months: 48; announced: 2019-05-18.
Open PhilanthropyYale University180,000.002019-03Scientific research/human health and wellbeinghttps://www.openphilanthropy.org/focus/scientific-research/human-health-and-wellbeing/yale-university-school-of-medicine-vascular-therapy Donation process: Discretionary grant

Intended use of funds (category): Direct project expenses

Intended use of funds: The grant page says that the grant is "to support research on the modification of vascular permeability by monoclonal antibodies against key regulatory proteins. Increased permeability might allow medicines to cross the blood-brain barrier and could accelerate the development of new therapies for neurogenerative diseases such as Alzheimer’s Disease, while decreased permeability could be useful in treating conditions such as swelling in stroke victims and sepsis."

Other notes: Announced: 2019-07-18.
Open PhilanthropyUniversity Health Network1,134,975.002019-02Scientific research/human health and wellbeinghttps://www.openphilanthropy.org/focus/scientific-research/university-health-network-preterm-birth-research Grant to the University Health Network, a Canadian research center affiliated with the University of Toronto, to support a randomized controlled trial investigating the efficacy of an intervention to reduce preterm birth in Malawi. Preterm birth is a leading cause of global under-five mortality, resulting in over 1 million deaths each year. The research will be led by Kevin Kain and Chloe McDonald. Announced: 2019-04-26.
Open PhilanthropySherlock Biosciences17,500,000.002019-01Scientific research/Biosecurity and pandemic preparednesshttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/sherlock-biosciences-research-viral-diagnostics Donation process: The Open Philanthropy Project's scientific advisors Chris Somerville and Heather Youngs were hopeful about viral diagnostics after hearing of research coming out of Feng Zhang's lab (Zhang would later co-found Sherlock Biosciences). When they ran into David Walt, they asked him if his new company (Sherlock Biosciences) would be interested in developing a viral diagnostic, and after consulting with his team, he said they would. This started the process of vetting Sherlock Biosciences for the grant

Intended use of funds (category): Direct project expenses

Intended use of funds: Grant to support the development of a diagnostic platform to identify any virus present in a patient sample.

Donor reason for selecting the donee: Chris Somerville and Heather Youngs have been interested in viral diagnostics because development of this technology could both reduce threats from viral pandemics and also benefit health care broadly. The selection of Sherlock Biosciences was because of their team and technology, which made it plausible that they could develop this technology

Other notes: The Open Philanthropy Project also recommended an additional investment in Sherlock Biosciences. Sherlock recently spun out of Harvard University’s Wyss Institute and the Broad Institute of MIT and Harvard. The launch of Sherlock Biosciences, and the funding by the Open Philanthropy Project, are discussed in Forbes at https://www.forbes.com/sites/elliekincaid/2019/03/21/with-launch-of-new-crispr-company-competition-extends-to-diagnostics/ More background explanation related to the grant is in the conversation blog post https://www.openphilanthropy.org/blog/explaining-our-bet-sherlock-biosciences-innovations-viral-diagnostics. Intended funding timeframe in months: 60; announced: 2019-03-21.
Open PhilanthropyGeorgia Institute of Technology50,000.002018-12Scientific research/transformative basic science/Innocentive challengehttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/georgia-institute-of-technology-saad-bhamla Grant to support research led by Dr. Saad Bhamla. Dr. Bhamla’s proposal, “Feathers as extreme water pumps,” was submitted in response to the Open Philanthropy Project's Innocentive challenge https://www.innocentive.com/ar/challenge/9934081 on bioinspiration and unusual biology. While this funding is not restricted to the execution of that proposal, the Open Philanthropy Project science team believes Dr. Bhamla's lab conducts other creative research, and wants to reward the spirit of creative science. Announced: 2019-02-12.
Open PhilanthropyThe University of Minnesota, Twin Cities150,000.002018-12Scientific research/transformative basic science/Innocentive challengehttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/university-of-minnesota-nanomaterials-research-led-by-prof-claudia-schmidt-dannert Grant to support nanomaterials research led by Professor Claudia Schmidt-Dannert. Professor Schmidt-Dannert’s proposal, titled “Genetically programmable, adhesive nanomaterials as patterned and functional surface coatings,” is the grand prize winner of the Open Philanthropy Project's Innocentive challenge https://www.innocentive.com/ar/challenge/9934081 on bioinspiration and unusual biology. The Open Philanthropy Project science team believes Professor Schmidt-Dannert could be able to design new materials with applications such as anti-fouling, anti-corrosion, and anti-freeze coatings, as well as coatings for biomedical applications. Announced: 2019-02-12.
Open PhilanthropyEicOsis Human Health, Inc.5,000,000.002018-11Scientific research/human health and wellbeinghttps://www.openphilanthropy.org/giving/grants/eicosis-human-health-inc-pain-research Grant to support clinical trials on a novel, non-opioid, oral therapy for neuropathic and inflammatory pain. The Open Philanthropy Project believes alternate therapies for chronic pain could help address the epidemic of opioid abuse and addiction. EicOsis previously received Blueprint funding https://neuroscienceblueprint.nih.gov/ for neuroscience research from the National Institutes of Health. This seed-stage investment is intended to support continued early research and development in the hopes that EicOsis can subsequently raise additional funds from other investors. Announced: 2019-02-15.
Open PhilanthropyUniversity of California, Berkeley200,000.002018-10Scientific researchhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/university-of-california-berkeley-research-on-drought-tolerant-rice-by-prof-brian-staskawicz Discretionary grant over three years to support the editing of the rice genome for increased drought tolerance led by Professor Brian Staskawicz. The work involves using CRISPR modifications to increase drought tolerance on Indian rice, and the goal is to address the problem of erratic rice yields which have negative impoact on the livelihoods of 100 million small farmers. The experiments are funded in part my a match from the Innovative Genomics Institute. This follows the plant pathology workshop grant of December 2016 https://www.openphilanthropy.org/focus/scientific-research/miscellaneous/uc-berkeley-plant-pathology-workshop. Announced: 2018-10-23.
Open PhilanthropyCDC Foundation1,044,501.002018-10Scientific researchhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/cdc-foundation-malaria-control-research-project-2018 Grant to support research on malaria control. This funding will be used to support work on the cryopreservation of mosquito larvae (which, if successful, would make it easier for researchers to maintain different strains of mosquitoes) and on RNA interference (which, if successful, would make it easier for researchers to avoid releasing female mosquitoes — which could potentially spread malaria — as part of field trials). Related previous grant https://www.openphilanthropy.org/focus/scientific-research/miscellaneous/cdc-foundation-malaria-control-research (September 2016) and related grant to Target Malaria https://www.openphilanthropy.org/focus/scientific-research (May 2017). Announced: 2018-10-30.
Open PhilanthropyDuke University2,550,171.002018-10Scientific researchhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/duke-university-CRISPR-Based-Epigenome-Editing-Tools Grant over three years to Duke University to develop tools to apply epigenome editing to refine genome wide association studies (GWAS). The work will be led by Charles Gersbach, the Rooney Family Associate Professor of Biomedical Engineering. This funding will support research to develop CRISPR-based epigenetic tools to interrogate thousands of regions of DNA, allowing for more nuanced studies of genomic regions identified through GWAS. The grant will also fund testing and verification of the tools by identifying loci implicated in schizophrenia, a poorly understood disorder. Announced: 2018-10-30.
Open PhilanthropyBoston Children's Hospital1,695,376.002018-10Scientific researchhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/boston-childrens-hospital-chronic-pain-research Grant over four years to conduct basic research into the epigenetics of chronic pain. The work will be led by Yi Zhang, a Howard Hughes Medical Institute investigator and the Fred Rosen Chair Professor of Genetics at Harvard Medical School and Boston Children’s Hospital. This funding will support research to identify 1) specific neurons in a region of the brain involved in processing environmental stimulation into associative learning; 2) changes in gene expression and epigenetic modification in neurons associated with chronic pain; and 3) feedback and modulatory processes that may be involved in resolving pain signals and neuronal sensitivity. Announced: 2018-11-27.
Open PhilanthropyUniversity of California, San Francisco1,021,318.002018-08Scientific researchhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/university-of-california-san-francisco-chronic-pain-research Grant over three years to support basic research on understanding the brain mechanisms that process pain messages and that contribute to the transition from acute to chronic pain after injury. The work will be led by Allan Basbaum, PhD, Professor and Chair of UCSF’s Department of Anatomy. This grant will allow UCSF to pursue an answer to the question of how the brain interprets various types of pain signals (e.g., heat, cold, mechanical) and itch, how these signals are regulated by different anesthetics and how they are altered when there is injury. Resolving these questions could facilitate the design of novel drugs that can block pain without also blocking consciousness. Announced: 2018-09-21.
Open PhilanthropyLife Sciences Research Foundation780,000.002018-04Scientific research/transformative basic sciencehttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/life-sciences-research-foundation-young-investigators Donation process: Discretionary grant

Intended use of funds (category): Direct project expenses

Intended use of funds: Grant "to support early-career investigators. The funds will support four postdoctoral fellows for three years apiece. The fellows have proposed research projects investigating immunology, virology, neurobiology, and tuberculosis."

Donor retrospective of the donation: The followup 2019 grant suggests that this grant would be considered a success

Other notes: Intended funding timeframe in months: 36; announced: 2018-05-03.
Open PhilanthropyVasoRx4,700,000.002018-04Scientific researchhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/vasorx-atherosclerosis-investment Investment to test a new therapy for vascular diseases such as atherosclerosis and pulmonary hypertension. The original amount was $1.6 million. In January 2019, $3.1 million was addded to the amount, and the total on the website was updated to reflect this. Announced: 2018-04-26.
Open PhilanthropyScience Philanthropy Alliance225,000.002018-04Scientific researchhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/science-philanthropy-alliance-general-support Discretionary grant over three years to join the Science Philanthropy Alliance, "a community of funders who work together to inspire new, emerging and current philanthropists to dedicate a portion of their philanthropy to basic science.". Announced: 2018-05-15.
Open PhilanthropyMIT Synthetic Neurobiology Group3,000,000.002018-02Scientific researchhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/massachusetts-institute-technology-synthetic-neurobiology-group-2018 Grant over two years. Grantee group led by Ed Boyden. Followup to March 2016 grant, and made for similar reasons as that first grant: https://www.openphilanthropy.org/focus/scientific-research/miscellaneous/massachusetts-institute-technology-synthetic-neurobiology-group. Announced: 2018-03-08.
Open PhilanthropyUniversity of California, San Francisco500,000.002018-02Biosecurity and pandemic preparedness/Scientific researchhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/ucsf-research-antiviral-activity-hsp90-inhibitors Grant to support research led by Dr. Raul Andino to test the broad spectrum antiviral potential of several drugs. The grant will allow Dr. Andino to carry out tests of the effectiveness of two commercial-quality drugs against five different viruses. Original grant amount of $320,000 in February 2018, and an additional $180,000 added in June 2018 (grant page updated around 2018-06-29). Announced: 2018-03-24.
Open PhilanthropyMamoreruinochi wo Mamorukai40,000.002018-02Scientific researchhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/mamoreruinochi-wo-mamorukai-legal-aid-for-scientists-in-japan Discretionary grant made by the Open Philanthropy Action Fund. Grantee, which translates roughly as Protect the Lives Protectable, is a Japanese organization that protects science journalists and scientists from attacks, insults, and litigation. Announced: 2018-07-06.
Open PhilanthropyBeth Israel Deaconess Medical Center2,934,400.002018-01Scientific researchhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/beth-israel-deaconess-medical-center-clinical-trial-sepsis-therapy Grant to support Dr. Michael Donnino to conduct a multicenter clinical trial of a therapy for severe sepsis. Announced: 2018-01-30.
Open Philanthropyprotocols.io200,000.002017-12Scientific researchhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/protocols-io-platform-improvements Discretionary grant to ZappyLab, Inc (doing business as “protocols.io”) to support improvements to the protocols.io platform, which provides open access for science methods. Announced: 2017-12-08.
Open PhilanthropyUniversity of Washington (Institute for Protein Design)11,367,500.002017-11Scientific researchhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/university-of-washington-universal-flu-vaccine Donation process: In the blog post https://www.openphilanthropy.org/blog/questions-we-ask-ourselves-making-grant Michael Levine describes the process of deciding the grant: "Through ongoing conversations, the original grant proposal focusing on the development of a universal flu vaccine evolved into an expanded grant incorporating work on a computational protein design system that we believe could have much broader utility if it makes it possible to rapidly design new vaccines or antiviral drugs."

Intended use of funds (category): Direct project expenses

Intended use of funds: Grant to support research on the use of computational protein design to develop a universal influenza vaccine. This work will be led by UW Professor David Baker, Ph.D., and UW Assistant Professor Neil King, Ph.D. In addition, part of this funding is intended to improve the Rosetta molecular modeling and design software originally developed in Baker’s lab. UW Assistant Professor Frank DiMaio, Ph.D., and others will work to improve Rosetta to better predict the properties of proteins

Donor reason for donating that amount (rather than a bigger or smaller amount): The blog post https://www.openphilanthropy.org/blog/questions-we-ask-ourselves-making-grant suggests a scope increase for the grant from being for a universal flu vaccine to being for improving computational protein design techniques as well.

Other notes: The grant is discussed in https://ssir.org/articles/entry/giving_in_the_light_of_reason as part of an overview of the Open Philanthropy Project grantmaking strategy. Intended funding timeframe in months: 60; announced: 2018-04-04.
Open PhilanthropyArizona State University6,421,402.002017-11Scientific research/transformative R01https://www.openphilanthropy.org/focus/scientific-research/miscellaneous/arizona-state-university-canine-clinical-trial-multivalent-cancer-vaccine Grant to be used in support of a canine clinical trial to assess the effectiveness of a multivalent, preventative cancer vaccine. The trial will test the cancer-prevention efficacy of a multi-valent frameshift peptide (FSP) vaccine, developed by Dr. Stephen Albert Johnston, in healthy, middle-aged pet dogs. The trial will be conducted under the direction of Dr. Douglas Thamm, Director of Clinical Research at the Flint Animal Cancer Center at Colorado State University. Part of a set of "second chance" grants by the Open Philanthropy Project for some rejected applications for the NIH Transformative R01 program https://commonfund.nih.gov/tra discussed at https://www.openphilanthropy.org/blog/our-second-chance-program-nih-transformative-research-applicants and https://www.nature.com/articles/d41586-017-08795-0. Announced: 2017-12-20.
Open PhilanthropyUniversity of California, Berkeley5,000,000.002017-08Scientific researchhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/uc-berkeley-aging-related-research-conboy Grant over five years to support research on the basic biology of aging-related diseases and impairments, led by Dr. Irina Conboy. Grant is a result of https://www.openphilanthropy.org/research/cause-reports/mechanisms-aging (investigation into mechanisms of aging). Announced: 2017-11-03.
Open PhilanthropyDuke University81,500.002017-06Scientific research/antiviral and inhibitor workhttps://www.openphilanthropy.org/focus/scientific-research/miscellaneous/duke-university-timothy-haystead-hsp70 Grant for work that will be led by Dr. Timothy Haystead, Professor of Pharmacology and Cancer Biology at the Duke University School of Medicine. Funding from this grant will allow Dr. Haystead to pay a specialized company to determine the molecular structure of the human Hsp70i protein in a complex with HS-72, and to hire a summer intern to support his antiviral and inhibitor work. The original grant amount was $49,500. In May 2018, $32,000 to the original award amount for additional work on the project. Announced: 2017-08-16.
Open PhilanthropyUniversity of Notre Dame2,054,142.002017-06Scientific research/transformative R01https://www.openphilanthropy.org/focus/scientific-research/miscellaneous/university-notre-dame-nanopore-protein-sequencing-development Grant over three years to the University of Notre Dame to support the development of an instrument that uses a sub-nanometer-diameter pore (i.e. a sub-nanopore) to read the amino acid sequence of whole protein molecules. The collaborative effort led by Dr. Gregory Timp involves researchers at the University of San Diego and Johns Hopkins University. Part of a set of "second chance" grants by the Open Philanthropy Project for some rejected applications for the NIH Transformative R01 program https://commonfund.nih.gov/tra discussed at https://www.openphilanthropy.org/blog/our-second-chance-program-nih-transformative-research-applicants and https://www.nature.com/articles/d41586-017-08795-0. Announced: 2017-12-20.
Open PhilanthropyUniversity of California, San Francisco825,000.002017-06Scientific research/transformative R01https://www.openphilanthropy.org/focus/scientific-research/miscellaneous/ucsf-liver-regeneration-experiments Grant over three years to the University of California, San Francisco (UCSF) to support research into the development of a stem cell treatment method for repairing or replacing damaged human livers. The work will be led by Tammy T. Chang, MD, PhD, assistant professor in the UCSF Department of Surgery. Part of a set of "second chance" grants by the Open Philanthropy Project for some rejected applications for the NIH Transformative R01 program https://commonfund.nih.gov/tra discussed at https://www.openphilanthropy.org/blog/our-second-chance-program-nih-transformative-research-applicants and https://www.nature.com/articles/d41586-017-08795-0. Announced: 2017-12-20.
Open PhilanthropyRockefeller University1,600,000.002017-04Scientific research/transformative R01https://www.openphilanthropy.org/focus/scientific-research/miscellaneous/rockefeller-university-viral-histone-mimics Grant to support research on viral histone mimics led by Professor Alexander Tarakhovsky. Professor Tarakhovsky has discovered a novel mechanism through which viruses may influence host gene expression: he found that in influenza H3N2, the non-structural 1 (NS1) protein acts to downregulate antiviral genes (i.e. weaken host defense systems) by mimicking human histone 3, which interferes with normal histone regulation in the host cell. Professor Tarakhovsky and his collaborators plan to use this grant to further explore this mechanism in the life cycle of the yellow fever virus and to determine whether the mechanism occurs in other host-virus interactions. Part of a set of "second chance" grants by the Open Philanthropy Project for some rejected applications for the NIH Transformative R01 program https://commonfund.nih.gov/tra discussed at https://www.openphilanthropy.org/blog/our-second-chance-program-nih-transformative-research-applicants and https://www.nature.com/articles/d41586-017-08795-0 Original grant amount $1.5 million; an additional $100,000 added to grant in July 2018 (page update: 2018-07-10). Announced: 2017-12-20.

Donation amounts by donee and year

Donee Donors influenced Cause area Metadata Total 2020 2019 2018 2017
Sherlock Biosciences Open Philanthropy (filter this donor) 17,500,000.00 0.00 17,500,000.00 0.00 0.00
University of Washington (Institute for Protein Design) Open Philanthropy (filter this donor) 11,367,500.00 0.00 0.00 0.00 11,367,500.00
Arizona State University Open Philanthropy (filter this donor) FB Tw WP Site 6,421,402.00 0.00 0.00 0.00 6,421,402.00
University of California, Berkeley Open Philanthropy (filter this donor) FB Tw WP Site 5,200,000.00 0.00 0.00 200,000.00 5,000,000.00
EicOsis Human Health, Inc. Open Philanthropy (filter this donor) 5,000,000.00 0.00 0.00 5,000,000.00 0.00
VasoRx Open Philanthropy (filter this donor) 4,700,000.00 0.00 0.00 4,700,000.00 0.00
Kyoto University Open Philanthropy (filter this donor) 4,000,000.00 0.00 4,000,000.00 0.00 0.00
MIT Synthetic Neurobiology Group Open Philanthropy (filter this donor) 3,000,000.00 0.00 0.00 3,000,000.00 0.00
Beth Israel Deaconess Medical Center Open Philanthropy (filter this donor) WP 2,934,400.00 0.00 0.00 2,934,400.00 0.00
Duke University Open Philanthropy (filter this donor) FB Tw WP Site 2,631,671.00 0.00 0.00 2,550,171.00 81,500.00
University of Michigan Open Philanthropy (filter this donor) FB Tw WP Site 2,500,000.00 0.00 2,500,000.00 0.00 0.00
University of California, Los Angeles Open Philanthropy (filter this donor) FB Tw WP Site 2,368,300.00 0.00 2,368,300.00 0.00 0.00
University of California, San Francisco Open Philanthropy (filter this donor) 2,346,318.00 0.00 0.00 1,521,318.00 825,000.00
University of Notre Dame Open Philanthropy (filter this donor) FB Tw WP Site 2,054,142.00 0.00 0.00 0.00 2,054,142.00
California Institute of Technology Open Philanthropy (filter this donor) FB Tw WP Site 2,000,000.00 0.00 2,000,000.00 0.00 0.00
Life Sciences Research Foundation Open Philanthropy (filter this donor) 1,950,000.00 0.00 1,170,000.00 780,000.00 0.00
Boston Children's Hospital Open Philanthropy (filter this donor) 1,695,376.00 0.00 0.00 1,695,376.00 0.00
Rockefeller University Open Philanthropy (filter this donor) FB Tw WP Site 1,600,000.00 0.00 0.00 0.00 1,600,000.00
University Health Network Open Philanthropy (filter this donor) WP 1,134,975.00 0.00 1,134,975.00 0.00 0.00
CDC Foundation Open Philanthropy (filter this donor) Tw Site 1,044,501.00 0.00 0.00 1,044,501.00 0.00
Engineers Without Borders USA Open Philanthropy (filter this donor) 500,000.00 0.00 500,000.00 0.00 0.00
Rita Allen Foundation Open Philanthropy (filter this donor) 495,000.00 0.00 495,000.00 0.00 0.00
Foundation for Food and Agricultural Research Open Philanthropy (filter this donor) Animal welfare FB Tw Site 444,000.00 444,000.00 0.00 0.00 0.00
Science Philanthropy Alliance Open Philanthropy (filter this donor) 225,000.00 0.00 0.00 225,000.00 0.00
protocols.io Open Philanthropy (filter this donor) 200,000.00 0.00 0.00 0.00 200,000.00
Yale University Open Philanthropy (filter this donor) FB Tw WP Site 180,000.00 0.00 180,000.00 0.00 0.00
The University of Minnesota, Twin Cities Open Philanthropy (filter this donor) 150,000.00 0.00 0.00 150,000.00 0.00
Georgia Institute of Technology Open Philanthropy (filter this donor) FB Tw WP Site 50,000.00 0.00 0.00 50,000.00 0.00
Mamoreruinochi wo Mamorukai Open Philanthropy (filter this donor) 40,000.00 0.00 0.00 40,000.00 0.00
Total ---- -- 83,732,585.00 444,000.00 31,848,275.00 23,890,766.00 27,549,544.00

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Donation amounts by donor and year for influencer Chris Somerville|Heather Youngs

Donor Donees Total 2020 2019 2018 2017
Open Philanthropy (filter this donee) Arizona State University (filter this donee), Beth Israel Deaconess Medical Center (filter this donee), Boston Children's Hospital (filter this donee), California Institute of Technology (filter this donee), CDC Foundation (filter this donee), Duke University (filter this donee), EicOsis Human Health, Inc. (filter this donee), Engineers Without Borders USA (filter this donee), Foundation for Food and Agricultural Research (filter this donee), Georgia Institute of Technology (filter this donee), Kyoto University (filter this donee), Life Sciences Research Foundation (filter this donee), Mamoreruinochi wo Mamorukai (filter this donee), MIT Synthetic Neurobiology Group (filter this donee), protocols.io (filter this donee), Rita Allen Foundation (filter this donee), Rockefeller University (filter this donee), Science Philanthropy Alliance (filter this donee), Sherlock Biosciences (filter this donee), The University of Minnesota, Twin Cities (filter this donee), University Health Network (filter this donee), University of California, Berkeley (filter this donee), University of California, Los Angeles (filter this donee), University of California, San Francisco (filter this donee), University of Michigan (filter this donee), University of Notre Dame (filter this donee), University of Washington (Institute for Protein Design) (filter this donee), VasoRx (filter this donee), Yale University (filter this donee) 83,732,585.00 444,000.00 31,848,275.00 23,890,766.00 27,549,544.00
Total -- 83,732,585.00 444,000.00 31,848,275.00 23,890,766.00 27,549,544.00

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Graph of spending by donee and year (cumulative)

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